Pharmaceutical Cleanroom Industry Articles

Exyte Builds First ExyCell® Facility in Shanghai

Exyte has successfully completed the construction of the first ExyCell® facility in China, the CliniMACS Cell Factory® of Miltenyi Biotec, a global provider of integrated solutions for Advanced Therapy Medical Products (ATMPs). The patented ExyCell technology was developed by Exyte as an end-to-end, integrated facility solution with standardized and modularized elements. These pre-configured and pre-fabricated modules enable fast-track construction thereby shortening time-to-market for new therapeutics and vaccines. The ExyCell facility is installed on the fourth floor of the ATLATL building located in the Zhangjiang High-Tech Park, and Miltenyi Biotec is now transferring production technology from Germany to China with regular operations for ATMP production is expected by autumn 2021. The facility will soon be open to visitors by appointment.

BrainStorm Increases Commercial Manufacturing Capacity

BrainStorm Cell Therapeutics Inc., a leading developer of cellular therapies for neurodegenerative diseases, announced today that is has received Good Manufacturing Practice (GMP) approval from the Israel Ministry of Health for three state-of-the-art cleanrooms…

WuXi Biologics Received Commercial Manufacturing License from German Health Authorities for its German Drug Product Facility

WuXi Biologics (“WuXi Bio”) (2269.HK), a global company with leading open-access biologics technology platforms, announced that it has received the License of Manufacturing Permit from German health authorities for its drug product facility (DP7) in Leverkusen, Germany. The permit successfully demonstrates for the first time that Premier Quality together with Record Speed WuXi Biologics consistently delivered in China can also be applied in global countries.

Quattroflow Increases Single-Use Pump Manufacturing Footprint with Construction of New Cleanroom

Quattroflow, part of PSG and Dover (NYSE: DOV), announced that it will increase manufacturing capacity for its single-use quaternary diaphragm pumps with the construction of a new ISO Class 7 cleanroom.
Expected to open in October 2021, the additional cleanroom will more than double the Quattroflow cleanroom space in Duisburg, Germany.

CPC Launches New MicroCNX Connectors, a First for Small-Volume Biopharma Processing

CPC Launches New MicroCNX Connectors, a First for Small-Volume Biopharma Processing

MicroCNX connectors are a critically important option for a range of bioprocessing, cell therapy and gene therapy workflows,.”Until now, cumbersome tube welding has been the only way to make sterile closed connections of very small-bore tubing. The MicroCNX connector represents a huge innovation for the industry.

Spectrum Plastics Group Announces Building Renovation & Cleanroom Expansion at Minneapolis Facility

Spectrum Plastics Group Announces Building Renovation & Cleanroom Expansion at Minneapolis Facility

Spectrum Plastics Group, a global solutions provider for development through scaled manufacturing of critical polymer-based components and devices for medical and other demanding markets, is excited to announce a significant renovation and cleanroom expansion project at its Minneapolis, MN facility.

Better enabled kidney exchanges for improved health and cost savings

Better enabled kidney exchanges for improved health and cost savings

Platforms for kidney exchanges such as the National Kidney Registry and the Alliance for Paired Donation provide a lifeline for people on the waiting list by expanding the pool of potential donors by matching potential recipients with living donors they’ve never met.

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Kinesin Proteins Study New Doors Open for Cancer Drug Innovation

Kinesin Proteins Study New Doors Open for Cancer Drug Innovation

The research involved kinesin proteins: tiny, protein-based motors that interact with microtubules inside cells. The motors convert chemical energy into mechanical energy to generate the directional movements and forces necessary to sustain life. Microtubules are microscopic tubular structures that have two distinct ends: a fast-growing plus end and a slow-growing minus ends. Microtubules help make up a cell’s skeleton.

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Flexible Packaging Cleanroom Expansion

Flexible Packaging Cleanroom Expansion

Today PPC Flexible Packaging announced it has completed the first phase of a greater than $2 million facilities and equipment investment aimed at expanding and further upgrading production capacities for its Precision Clean™ cleanroom packaging business. The company purchased its Buffalo Grove based business as Fisher Container Corporation in February 2017.

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Herpes Linked to Alzheimer’s Disease

Herpes Linked to Alzheimer’s Disease

“It was as long ago as 1991 when we discovered that, in many elderly people infected with HSV1, the virus is present also in the brain, and then in 1997 that it confers a strong risk of Alzheimer’s disease in the brain of people who have a specific genetic factor.”

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Neural Circuits Controlled By Sound Waves

Neural Circuits Controlled By Sound Waves

In the maze of our brains, there are various pathways by which neural signals travel. These pathways can go awry in patients with neurological and psychiatric diseases and disorders, including epilepsy, Parkinson’s, and obsessive-compulsive disorder. Researchers have developed new therapeutic strategies to more precisely target neural pathways involved in these conditions, but they often require surgery. 

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Gene Editing Therapy Made Safer With New CRISPR Technique

Gene Editing Therapy Made Safer With New CRISPR Technique

Scientists from The University of Texas at Austin took an important step toward safer gene editing cures for life-threatening disorders, from cancer to HIV to Huntington’s disease, by developing a technique that can spot editing mistakes a popular tool known as CRISPR makes to an individual’s genome. The research appears today in the journal Cell.

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Immune Cells Boosted by Nanoparticles

Immune Cells Boosted by Nanoparticles

By developing nanoparticle “backpacks” that hold immune-stimulating drugs, and attaching them directly to T cells, the MIT engineers showed in a study of mice that they could enhance those T cells’ activity without harmful side effects. In more than half of the treated animals, tumors disappeared completely.

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Biotechnology Innovation Platform Launched by HKU

Biotechnology Innovation Platform Launched by HKU

Biotechnology Innovation Platform Launch expected to become a national-level technology startup incubator. It aims to host at least 50 spinoff companies and commercialize the results of at least 10 HKU research projects within five years. The platform will focus on key areas including cancer treatment, medical devices and infectious disease treatment.

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